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FDA-approved drugEndocrine Signaling ResearchTH9507

Tesamorelin

Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH). It has been studied in randomized, double-blind, placebo-controlled human trials published in peer-reviewed journals.

Evidence: strong · Peer-reviewed randomized human trials

At a glance

Class
GHRH analog
Developer
Theratechnologies
FDA status
FDA-approved prescription drug (brands: Egrifta SV, Egrifta WR). This page covers the research compound only.
Human data
Randomized, double-blind, placebo-controlled trials (design-level only)
Animal / lab data
Little published animal work located; research is predominantly human

Where it’s been studied

1
  • 1LiverLiver fat imaging endpoint, human (2014)

Mechanism studied

Established: tesamorelin is a synthetic analog of growth hormone-releasing factor (GHRH), which acts at pituitary GHRH receptors to stimulate growth hormone release [1].

What the research shows

StudyModelReported resultSource
Randomized trial with safety extension [1]Human
404 adults, randomized 2:1, double-blind, placebo-controlled, 6 months plus 6-month re-randomized extension
Primary endpoint: imaging measure (see publication). Published.Peer-reviewed
J Acquir Immune Defic Syndr 2010
Visceral and liver fat trial [2]Human
50 adults, randomized, double-blind, placebo-controlled, 6 months
Primary endpoints: imaging measures (see publication). Published.Peer-reviewed
JAMA 2014

Human trials are listed for research context only; outcomes are reported in the linked publications. Animal and lab results do not establish effects in humans.

Supply

PureLab does not supply this compound. This page summarizes published research only.

More in Endocrine Signaling Research

Sources

  1. Published source (2010). pubmed.ncbi.nlm.nih.gov Source
  2. Stanley TL et al. (2014) Source
For research use only. Not for human or veterinary use. Not a drug, food or cosmetic, and not intended to diagnose, treat, cure or prevent any disease. This library summarizes published research for educational purposes. PureLab Performance Inc.